Clinical Protocol

7-Day Acetoacetate (Ketone) Plan

A structured ketogenic protocol designed to boost the production of Acetoacetate, the primary ketone body produced by the liver.

Protocol Objectives
Strict Carb Limit

Acetoacetate is produced only when insulin is low. Keep total carbs under 20g/day to unlock this pathway.

MCT Oil Use

MCTs are the fastest precursor to acetoacetate. Include 1-2 tbsp daily.

Fasting Windows

Intermittent fasting (16:8) depletes liver glycogen, signaling the liver to begin acetoacetate synthesis.

Moderate Protein

Excess protein can be converted to glucose. Keep protein moderate (0.8g/lb lean mass) to maintain ketosis.

Day 1 Entry to Ketosis
Breakfast
Coffee with 1tbsp MCT Oil
Direct fuel for acetoacetate.
Lunch
Bacon & Spinach Salad
High fat, low carb greens.
Dinner
Ribeye Steak with Butter
Fatty meat is essential.
Day 2 Fat Adaptation
Breakfast
3 Eggs Scrambled in Ghee
Ghee is pure fat.
Lunch
Salmon Salad (Mayo Base)
Use olive oil mayo.
Dinner
Pork Belly & Bok Choy
High fat cut.
Day 3 Deep Ketosis
Breakfast
Macadamia Nuts
Ideal keto snack/meal.
Lunch
Salami & Cream Cheese Roll-ups
Zero carb lunch.
Dinner
Chicken Thighs (Skin On)
Roasted in avocado oil.
Day 4 MCT Boost
Breakfast
MCT Oil Smoothie (Avocado/Spinach)
Creamy and ketogenic.
Lunch
Burger Patty with Cheese
No bun, obviously.
Dinner
Lamb Chops with Rosemary
Fatty red meat.
Day 5 Fasting Signal
Breakfast
Black Coffee (Skip Meal)
Extend fast to 18 hours.
Lunch
Cobb Salad with Extra Avocado
Break fast with fat.
Dinner
Sardines in Olive Oil
Zero carb protein.
Day 6 Electrolyte Balance
Breakfast
Salted Pecans & Cheese
Salt helps retention.
Lunch
Egg Salad Lettuce Boats
Classic keto lunch.
Dinner
Beef Stir-fry (No Sauce)
Use salt/pepper/garlic only.
Day 7 Maintenance
Breakfast
Omelet with Sausage
High satiety.
Lunch
Leftover Pork Belly
Fatty leftovers.
Dinner
Duck Breast & Asparagus
Duck fat is premium fuel.

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Protocol Guidelines & Science
Acetoacetate vs Beta-Hydroxybutyrate

Acetoacetate is the first ketone produced. It is often converted to BHB. To measure success, use urine strips (which measure acetoacetate) in the early stages.

Hydration

Ketosis sheds water weight. Drink 3L+ of water daily to support kidney function and ketone circulation.

Scientific References:
1. Cahill Jr, G. F. (2006). 'Fuel metabolism in starvation.' Annual Review of Nutrition.
2. Laffel, L. (1999). 'Ketone bodies: a review of physiology, pathophysiology and application of monitoring to diabetes.' Diabetes/Metabolism Research and Reviews.
3. Volek, J. S., et al. (2002). 'Body composition and hormonal responses to a carbohydrate-restricted diet.' Metabolism.